Immune & Antimicrobial
Thymulin

Thymulin is a thymus hormone with a metal at its centre: without a zinc atom bound to it the molecule does nothing at all, so its activity reads out zinc status directly, which is why thymulin falls in zinc deficiency and in old age. In mice it restrains the smouldering inflammation that accompanies ageing and improves responses to cancer immunotherapy. In humans it has only ever been measured: no human trial is on file, no safety profile has been characterised, and no dose has been validated. Doses do circulate for it, and nothing in the record supports any of them.
Last updated
Mechanism
Supports T-cell differentiation, NK-cell activity, and neuroendocrine immune crosstalk.
Reported effects
What sources associate with this compound. Reported categories, not outcomes we have graded — each would need its own citation and rung.
- T-cell maturation
- Immune-stress balance
- NK-cell support
Dosing on file unverified
5-10 mg daily, cycled 1–2 weeks
| Reported dose | Volume | Draw |
|---|---|---|
| Low — 5 mg | 1 mL | 100 units |
| High — 10 mg | 2 mL | 200 units |
What that assumes. Assumes 10 mg in 2 mL (5000 mcg/mL) drawn on a U-100 barrel — the preset on this record, not a recommendation and not the only way to mix it. Change the vial mass, the diluent or the barrel and every number in this table changes. Run your own.
Carried from a source that labels it unverified, and reproduced with that label attached. A record of what is reported, not a recommendation. No citation on this page establishes it.
Reconstitution
| Vial | Diluent | Concentration | Typical dose | Draw |
|---|---|---|---|---|
| 10 mg | 2 mL | 5000 mcg/mL | 5000 mcg | 100 units |
mass ÷ diluent = concentration; dose ÷ concentration = volume; volume × the syringe factor = units on the barrel (100 for U-100, 40 for U-40). Run your own numbers.
Literature on file 7
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in vitro
Serum thymulin in human zinc deficiency (Journal of Clinical Investigation 1988, cited 272x) graded on: an in-vitro system — read from the indexed abstract — “assay”
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review or editorial
Targeting Leukopoiesis: Pharmacological and Biotechnological Strategies for the Treatment of Leukopenia. graded on: indexed as "review-article" - secondary literature, not a study — “review-article”
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review or editorial
Maternal Thymus Adaptations and Hormone Regulation During Pregnancy. graded on: indexed as "review-article" - secondary literature, not a study — “review-article”
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review or editorial
Micro nutrients as immunomodulators in the ageing population: a focus on inflammation and autoimmunity. graded on: indexed as "review-article" - secondary literature, not a study — “review-article”
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animal in vivo
Thymulin restrains age-associated myeloid inflammation and enhances cancer immunotherapy. graded on: an animal model — read from the indexed abstract — “Mice”
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animal in vivo
Protective effect of exogenous peroxiredoxin 6 and thymic peptide thymulin on BBB conditions in an experimental model of multiple sclerosis. graded on: an animal model — read from the indexed abstract — “Mice”
Not graded
1 citation whose study design could not be read from the title. Left ungraded rather than guessed at.
- not graded
Identity
Skeletal formulathe canonical depiction
Drawn by PubChem from CID 71300623, the identifier on this record.
- Molecular weight
- 858.9
- Molecular formula
- C33H54N12O15
- CAS number
- 78922-62-0
- PubChem CID
- 71300623
- InChI key
- LIFNDDBLJFPEAN-YTAPOSPOSA-N
- Sequence
- XAKSQGGSN
- SMILES
- C[C@@H](C(=O)N[C@@H](CCCCN)C(=O)NC(CO)C(=O)N[C@@H](CCC(=O)N)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)N)C(=O)O)NC(=O)[C@@H]1CCC(=O)N1
- InChI
- InChI=1S/C33H54N12O15/c1-15(39-29(55)18-6-8-24(50)40-18)27(53)42-16(4-2-3-9-34)30(56)45-21(14-47)32(58)43-17(5-7-22(35)48)28(54)38-11-25(51)37-12-26(52)41-20(13-46)31(57)44-19(33(59)60)10-23(36)49/h15-21,46-47H,2-14,34H2,1H3,(H2,35,48)(H2,36,49)(H,37,51)(H,38,54)(H,39,55)(H,40,50)(H,41,52)(H,42,53)(H,43,58)(H,44,57)(H,45,56)(H,59,60)/t15-,16-,17-,18-,19-,20-,21?/m0/s1
Classified as
- Thymic Immune Modulationmechanism
- This holds some of the oldest peptide literature on the site, much of it decades old and to standards that would not pass review today. The rung is doing real work here rather than decorating an already strong record.
- Subcutaneousroute
- This is the route the reconstitution arithmetic assumes. Mass divided by diluent volume gives concentration, dose divided by concentration gives volume, and volume in mL multiplied by 100 gives units on a U-100 barrel: 5 mg in 2 mL is 2.5 mg/mL, and 0.25 mg comes out at 0.1 mL, which is 10 units.
Also called
- Thymulin
Notes unverified prose
No FDA approval; no validated human dose; no characterized human safety profile; no human clinical trials
Not on file 1
All 8 tracked fields hold a value on this record. 1 further absence is named below. A blank field is a bug; a named absence is a finding.
- half-lifenothing we hold supplies it
Each field links to every other record missing the same thing. The full ledger holds 765 gaps across 163 records.
Listed prices 14
What 12 shops we track listed for Thymulin, read from their own public catalogues on 2026-09-14. We take no commission on these and they are not ranked by any payment — how vendors are scored.
Compare prices14 listings from 12 shops
| Vendor | Size | Price | Per mg |
|---|---|---|---|
| AMC Essentials | 10 mg | $39.99 USD | $4.00/mg |
| Peptides.GG | 10 mg | $40.00 USD | $4.00/mg |
| PeptiFy Labs | 10 mg | $51.99 USD | $5.20/mg |
| BioLongevity Labs | 10 mg | $64.97 USD | $6.50/mg |
| Oath Peptides | 10 mg | $65.00 USD | $6.50/mg |
| Oath Research | 10 mg | $65.00 USD | $6.50/mg |
| Oath Peptides | 5 mg | $45.00 USD | $9.00/mg |
| Oath Research | 5 mg | $45.00 USD | $9.00/mg |
| Southern Aminos | 10 mg | $93.75 USD |
$9.38/mg |
| Real Peptides | size not listed | $48.00 USD | — |
| Alpha Omega Peptide | size not listed | $84.00 USD | — |
| SimplePeptide | size not listed | $84.00 USD | — |
| Vendor | Size | Price | Per mg |
|---|---|---|---|
| Peptide Cart | 10 mg | $49.99 CAD | $5.00/mg |
| VPeptide Canada | 20 mg | $100.00 CAD | $5.00/mg |
None of these shops lists your destination. Choose “Show all” to see every listing we hold.
Prices are the vendor's own listing, reproduced with the date we read it — never converted between currencies, and compared per milligram only where the vendor states the vial size.