PEPTIDE CORPUS

Immune & Antimicrobial

Thymulin

Space-filling model of Thymulin

Thymulin is a thymus hormone with a metal at its centre: without a zinc atom bound to it the molecule does nothing at all, so its activity reads out zinc status directly, which is why thymulin falls in zinc deficiency and in old age. In mice it restrains the smouldering inflammation that accompanies ageing and improves responses to cancer immunotherapy. In humans it has only ever been measured: no human trial is on file, no safety profile has been characterised, and no dose has been validated. Doses do circulate for it, and nothing in the record supports any of them.

Last updated

Studied forT-cell maturation · Immune-stress balance · NK-cell support
Evidence on file2 animal studies · 1 in-vitro study · 1 citation not yet graded
Strongest sourceThymulin restrains age-associated myeloid inflammation and enhances cancer immunotherapy. (animal study)

Mechanism

Supports T-cell differentiation, NK-cell activity, and neuroendocrine immune crosstalk.

Reported effects

What sources associate with this compound. Reported categories, not outcomes we have graded — each would need its own citation and rung.

  • T-cell maturation
  • Immune-stress balance
  • NK-cell support

Dosing on file unverified

5-10 mg daily, cycled 1–2 weeks

Reported doseVolumeDraw
Low — 5 mg1 mL100 units
High — 10 mg2 mL200 units

What that assumes. Assumes 10 mg in 2 mL (5000 mcg/mL) drawn on a U-100 barrel — the preset on this record, not a recommendation and not the only way to mix it. Change the vial mass, the diluent or the barrel and every number in this table changes. Run your own.

Carried from a source that labels it unverified, and reproduced with that label attached. A record of what is reported, not a recommendation. No citation on this page establishes it.

Reconstitution

VialDiluentConcentrationTypical doseDraw
10 mg2 mL5000 mcg/mL5000 mcg100 units

mass ÷ diluent = concentration; dose ÷ concentration = volume; volume × the syringe factor = units on the barrel (100 for U-100, 40 for U-40). Run your own numbers.

Literature on file 7

Not graded

1 citation whose study design could not be read from the title. Left ungraded rather than guessed at.

Identity

PubChem CID 71300623 computed 3D conformer Space-filling 3D model of Thymulin, carbon grey, nitrogen blue, oxygen red
Built from the SMILES on this record — the atoms and bonds are exact. The shape is one computed low-energy pose, not a measured structure: a flexible peptide in solution has no single conformation, and where the SMILES leaves a stereocentre undefined the pose commits to one arbitrarily. The skeletal formula below claims connectivity and nothing more, which is what we actually know.
Skeletal formulathe canonical depiction
2D chemical structure of Thymulin

Drawn by PubChem from CID 71300623, the identifier on this record.

Molecular weight
858.9
Molecular formula
C33H54N12O15
CAS number
78922-62-0
PubChem CID
71300623
InChI key
LIFNDDBLJFPEAN-YTAPOSPOSA-N
Sequence
XAKSQGGSN
SMILES
C[C@@H](C(=O)N[C@@H](CCCCN)C(=O)NC(CO)C(=O)N[C@@H](CCC(=O)N)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)N)C(=O)O)NC(=O)[C@@H]1CCC(=O)N1
InChI
InChI=1S/C33H54N12O15/c1-15(39-29(55)18-6-8-24(50)40-18)27(53)42-16(4-2-3-9-34)30(56)45-21(14-47)32(58)43-17(5-7-22(35)48)28(54)38-11-25(51)37-12-26(52)41-20(13-46)31(57)44-19(33(59)60)10-23(36)49/h15-21,46-47H,2-14,34H2,1H3,(H2,35,48)(H2,36,49)(H,37,51)(H,38,54)(H,39,55)(H,40,50)(H,41,52)(H,42,53)(H,43,58)(H,44,57)(H,45,56)(H,59,60)/t15-,16-,17-,18-,19-,20-,21?/m0/s1

Classified as

Thymic Immune Modulationmechanism
This holds some of the oldest peptide literature on the site, much of it decades old and to standards that would not pass review today. The rung is doing real work here rather than decorating an already strong record.
Subcutaneousroute
This is the route the reconstitution arithmetic assumes. Mass divided by diluent volume gives concentration, dose divided by concentration gives volume, and volume in mL multiplied by 100 gives units on a U-100 barrel: 5 mg in 2 mL is 2.5 mg/mL, and 0.25 mg comes out at 0.1 mL, which is 10 units.

Also called

  • Thymulin

Notes unverified prose

No FDA approval; no validated human dose; no characterized human safety profile; no human clinical trials

Not on file 1

All 8 tracked fields hold a value on this record. 1 further absence is named below. A blank field is a bug; a named absence is a finding.

Each field links to every other record missing the same thing. The full ledger holds 765 gaps across 163 records.

Listed prices 14

What 12 shops we track listed for Thymulin, read from their own public catalogues on 2026-09-14. We take no commission on these and they are not ranked by any payment — how vendors are scored.

Compare prices14 listings from 12 shops
Listed in USD
VendorSizePricePer mg
AMC Essentials 10 mg $39.99 USD $4.00/mg
Peptides.GG 10 mg $40.00 USD $4.00/mg
PeptiFy Labs 10 mg $51.99 USD $5.20/mg
BioLongevity Labs 10 mg $64.97 USD $6.50/mg
Oath Peptides 10 mg $65.00 USD $6.50/mg
Oath Research 10 mg $65.00 USD $6.50/mg
Oath Peptides 5 mg $45.00 USD $9.00/mg
Oath Research 5 mg $45.00 USD $9.00/mg
Southern Aminos 10 mg $93.75 USD $125.00 USD $9.38/mg
Real Peptides size not listed $48.00 USD —
Alpha Omega Peptide size not listed $84.00 USD —
SimplePeptide size not listed $84.00 USD —
Listed in CAD
VendorSizePricePer mg
Peptide Cart 10 mg $49.99 CAD $5.00/mg
VPeptide Canada 20 mg $100.00 CAD $5.00/mg

Prices are the vendor's own listing, reproduced with the date we read it — never converted between currencies, and compared per milligram only where the vendor states the vial size.

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