Oxytocin

Mechanism

OXTR agonism affecting threat processing, social salience, and autonomic tone.

Reported effects

What sources associate with this compound. Reported categories, not outcomes we have graded — each would need its own citation and rung.

• Anxiety/social-context support
• HPA recovery
• Libido research

Half-life, storage & sport

Elimination half-life

1 to 6 minutes (human, IV) — study. PITOCIN FDA prescribing information, clinical pharmacology.

Storage

Reconstituted: Solution (Pitocin injection USP, not lyophilized). Store 20-25C. — source. FDA label, Pitocin.

In sport (WADA 2026)

Not prohibited. Approved medicine and not named in S2 or any other class. The word oxytocin does not appear in the 2026 list text. the list

The half-life on file is 4 min, measured intravenously. On the schedule this record states — every 6 h — each dose has fallen to under 0.1% of its own peak by the time the next is given. Nothing accumulates, and there is no loading phase to run.

The half-life was measured by a route this is not given by. That makes it a lower bound rather than an estimate: absorption from an injection site goes on supplying the blood after an intravenous bolus would have cleared, so the real curve is flatter and lasts longer than the one drawn here. It is never shorter.

The rise is not modelled and the axis is not a blood level. No absorption rate constant and no volume of distribution are on file, so each dose appears at full height the instant it is given, and the axis is percent of this compound's own peak.

Literature on file 5

• human observational
  Oxytocin increases trust in humans (Nature 2005, cited 2726x) graded on: indexed as a clinical trial, design not stated — “Clinical Trial”
• review or editorial
  The Oxytocin Receptor System: Structure, Function, and Regulation (Physiological Reviews 2001, cited 2513x) graded on: indexed as "Review" - secondary literature, not a study — “Review”

Not graded

3 citations whose study design could not be read from the title. Left ungraded rather than guessed at.

• not graded
  NCT04551482: Oxytocin as a Neuroendocrine Therapy for Obesity in Youth graded on: NCT04551482 is recruiting and has posted no results - a registration, not a reported outcome — “NCT04551482”
• not graded
  NCT04789148: Effects of Intranasal Oxytocin in Patients With Arginine-vasopressin Deficiency - A Pilot Study graded on: NCT04789148 is recruiting and has posted no results - a registration, not a reported outcome — “NCT04789148”
• not graded
  NCT03860233: Benefits of Oxytocin in OSA Patients Using CPAP graded on: NCT03860233 is recruiting and has posted no results - a registration, not a reported outcome — “NCT03860233”

Identity

PubChem CID 439302 computed 3D conformer

Skeletal formulathe canonical depiction

Drawn by PubChem from CID 439302, the identifier on this record.

Molecular weight

1007.2

Molecular formula

C43H66N12O12S2

CAS number

50-56-6

PubChem CID

439302

UniProt

P01178

InChI key

XNOPRXBHLZRZKH-DSZYJQQASA-N

SMILES

CC[C@H](C)[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N1)CC2=CC=C(C=C2)O)N)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N

InChI

InChI=1S/C43H66N12O12S2/c1-5-22(4)35-42(66)49-26(12-13-32(45)57)38(62)51-29(17-33(46)58)39(63)53-30(20-69-68-19-25(44)36(60)50-28(40(64)54-35)16-23-8-10-24(56)11-9-23)43(67)55-14-6-7-31(55)41(65)52-27(15-21(2)3)37(61)48-18-34(47)59/h8-11,21-22,25-31,35,56H,5-7,12-20,44H2,1-4H3,(H2,45,57)(H2,46,58)(H2,47,59)(H,48,61)(H,49,66)(H,50,60)(H,51,62)(H,52,65)(H,53,63)(H,54,64)/t22-,25-,26-,27-,28-,29-,30-,31-,35-/m0/s1

Classified as

Intranasalroute

A nasal device delivers a fixed volume per spray, so concentration rather than syringe volume sets the amount per spray, and a mass figure on a record is not usable until you know how many actuations it was divided across.

Also called

• Oxytocin

Listed prices 155

What 99 shops we track listed for Oxytocin, read from their own public catalogues on 2026-09-14. We take no commission on these and they are not ranked by any payment — how vendors are scored.

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