DSIP

Mechanism

Modulates sleep-arousal networks through hypothalamic signaling.

Reported effects

What sources associate with this compound. Reported categories, not outcomes we have graded — each would need its own citation and rung.

• Faster sleep onset
• Fewer awakenings
• Sleep continuity

Reconstitution

mass ÷ diluent = concentration; dose ÷ concentration = volume; volume × the syringe factor = units on the barrel (100 for U-100, 40 for U-40). Run your own numbers.

Half-life, storage & sport

Elimination half-life

4.0 +/- 0.7 min (dog, IV) — study. Neuroendocrinology 1984; 4 anesthetized dogs, 1 or 2 mg DSIP.

Storage

Lyophilised: Stable at room temperature ~3 weeks; store desiccated below -18C. Reconstituted: 4C for 2-7 days; below -18C for future use; 0.1% HSA/BSA for long term; avoid freeze-thaw. — source. ProSpec technical datasheet. Supplier handling recommendation for research-grade lyophilate, not a per-compound stability study.

In sport (WADA 2026)

Prohibited, at all times — S0 catch-all. the list Not named; no therapeutic approval anywhere.

The half-life on file is 4 min, measured intravenously in dogs. On the schedule this record states — daily — each dose has fallen to under 0.1% of its own peak by the time the next is given. Nothing accumulates, and there is no loading phase to run.

The measurement is not human. It was made in dog, and small mammals clear peptides faster than people do — so this is the fastest plausible shape rather than the expected one.

The rise is not modelled and the axis is not a blood level. No absorption rate constant and no volume of distribution are on file, so each dose appears at full height the instant it is given, and the axis is percent of this compound's own peak.

Literature on file 6

• review or editorial
  Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions. graded on: indexed as "review-article" - secondary literature, not a study — “review-article”
• review or editorial
  Therapeutic Peptides in Aesthetic, Metabolic and Endocrine Conditions: Effects, Safety, Clinical Applications, and Future Perspectives. graded on: indexed as "review-article" - secondary literature, not a study — “review-article”
• animal in vivo
  One-Step Maleimide-Based Dual Functionalization of Protein N-Termini. graded on: an animal model — read from the indexed abstract — “mice”

Not graded

3 citations whose study design could not be read from the title. Left ungraded rather than guessed at.

• not graded
  Delta sleep-inducing peptide (2001, cited 13x)
• not graded
  Synergies from a distance: Inspirations from the struggles of Dr James M Krueger.
• not graded
  Deuterium Labeling of Isoaspartic and Isoglutamic Acids for Mass Spectrometry Analysis.

Identity

PubChem CID 68816 computed 3D conformer

Skeletal formulathe canonical depiction

Drawn by PubChem from CID 68816, the identifier on this record.

Molecular weight

848.8

Molecular formula

C35H48N10O15

CAS number

62568-57-4

PubChem CID

68816

InChI key

ZRZROXNBKJAOKB-GFVHOAGBSA-N

Sequence

WAGGDASGE

SMILES

C[C@@H](C(=O)NCC(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)O)NC(=O)[C@H](CC1=CNC2=CC=CC=C21)N

InChI

InChI=1S/C35H48N10O15/c1-16(41-32(56)20(36)9-18-11-37-21-6-4-3-5-19(18)21)30(54)39-12-25(47)38-13-26(48)44-23(10-29(52)53)34(58)42-17(2)31(55)45-24(15-46)33(57)40-14-27(49)43-22(35(59)60)7-8-28(50)51/h3-6,11,16-17,20,22-24,37,46H,7-10,12-15,36H2,1-2H3,(H,38,47)(H,39,54)(H,40,57)(H,41,56)(H,42,58)(H,43,49)(H,44,48)(H,45,55)(H,50,51)(H,52,53)(H,59,60)/t16-,17-,20-,22-,23-,24-/m0/s1

Classified as

Intranasalroute

A nasal device delivers a fixed volume per spray, so concentration rather than syringe volume sets the amount per spray, and a mass figure on a record is not usable until you know how many actuations it was divided across.

Intravenousroute

A large share of the pharmacokinetic numbers attached to peptide records, half-life in particular, come from intravenous studies and often from animals. Those numbers describe an intravenous curve and do not transfer unchanged to a depot under the skin.

Also called

• DSIP
• DSIP (Delta Sleep-Inducing Peptide)

Listed prices 264

What 165 shops we track listed for DSIP, read from their own public catalogues on 2026-09-14. We take no commission on these and they are not ranked by any payment — how vendors are scored.

Share this record