Tissue Repair & Regeneration
Collagen Peptides
Collagen peptides are collagen — cow hide, fish skin, bone — cut into fragments small enough to survive digestion; pieces such as prolyl-hydroxyproline turn up in the bloodstream afterwards. Unusually for this corpus, the randomised trials exist and mostly point the same way: a meta-analysis of four placebo-controlled trials in 507 adults with knee osteoarthritis found pain lower on collagen peptides, a trial in 120 people with pressure ulcers found the treated arm differed from placebo on wound scores, and a crossover trial in 20 adults with Achilles tendinopathy found a larger gain than placebo alongside a strengthening programme. The skin case is the softest of the set: a 2026 meta-analysis of 19 trials puts the pooled wrinkle effect at modest.
Last updated
Mechanism
Digested to small peptides such as prolyl-hydroxyproline that reach the dermis and stimulate fibroblast collagen and hyaluronan synthesis.
Reported effects
What sources associate with this compound. Reported categories, not outcomes we have graded — each would need its own citation and rung.
- Skin elasticity research
- Skin hydration support
- Wound healing context
- Joint comfort research
Dosing on file unverified
2.5 - 15 g/day
Carried from a source that labels it unverified, and reproduced with that label attached. A record of what is reported, not a recommendation. No citation on this page establishes it.
Literature on file 4
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human observational
Oral Collagen Supplementation: A Systematic Review of Dermatological Applications (J Drugs Dermatol 2019) graded on: a synthesis of human studies — “Systematic Review”
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human observational
Collagen supplementation for skin health: A mechanistic systematic review (Journal of Cosmetic Dermatology 2020, cited 54x) graded on: a synthesis of human studies — “systematic review”
Not graded
2 citations whose study design could not be read from the title. Left ungraded rather than guessed at.
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not graded
NCT07529249: Evaluation of Oral Collagen Peptides on Skin Barrier Function in Women With Dry Skin graded on: NCT07529249 is recruiting and has posted no results - a registration, not a reported outcome — “NCT07529249”
- not graded
Notes unverified prose
Numerous RCTs; NCT07529249 (2 doses, 3 months); 2.5 g/day, 5 g/day, 10 g/day used in published trials; PMID: 30681787; Systematic review; multiple RCTs
Not on file 9
8 of the 8 fields we track hold nothing on this record, and each says why. 1 further absence is named below. A blank field is a bug; a named absence is a finding.
- molecular weightnothing we hold supplies it
- molecular formulanothing we hold supplies it
- CAS registry numbernothing we hold supplies it
- PubChem identifiernothing we hold supplies it
- amino-acid sequencenot applicable to this compound
- SMILES stringnothing we hold supplies it
- InChInothing we hold supplies it
- InChI keynothing we hold supplies it
- half-lifenothing we hold supplies it
Each field links to every other record missing the same thing. The full ledger holds 765 gaps across 163 records.
Listed prices 1
What 1 shop we track listed for Collagen Peptides, read from their own public catalogues on 2026-09-14. We take no commission on these and they are not ranked by any payment — how vendors are scored.
Compare prices1 listing from 1 shop
| Vendor | Size | Price | Per mg |
|---|---|---|---|
| Mountainside Medical | size not listed | $14.95 USD |
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None of these shops lists your destination. Choose “Show all” to see every listing we hold.
Prices are the vendor's own listing, reproduced with the date we read it — never converted between currencies, and compared per milligram only where the vendor states the vial size.