Tissue Repair & Regeneration
Cartilage Peptides
Cartilage peptides are not one molecule but a powder: fish or animal cartilage taken apart by enzymes into short collagen fragments plus chondroitin sulphate. The logic is blunt — feed the joint the material a joint is made of, on the argument that the fragments serve as both raw stock and signal for the cells that maintain cartilage. The human study on file is open-label and multi-centre: 33 adults with knee discomfort took 1,000 mg of fish cartilage hydrolysate daily for three months and their knee pain and function scores improved, with no placebo arm to measure that against. The authors say so themselves and call for a randomised trial.
Last updated
Mechanism
Supplies low-molecular-weight collagen peptides and chondroitin sulphate studied as substrates and signals for chondrocyte matrix synthesis.
Reported effects
What sources associate with this compound. Reported categories, not outcomes we have graded — each would need its own citation and rung.
- Knee comfort research
- Joint function research
- Cartilage matrix support
Dosing on file unverified
1,000 - 3,000 mg/day (hydrolyzed fish cartilage, supplement)
Carried from a source that labels it unverified, and reproduced with that label attached. A record of what is reported, not a recommendation. No citation on this page establishes it.
Literature on file 3
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animal in vivo
Preparation, typical structural characteristics and relieving effects on osteoarthritis of squid cartilage type II collagen peptides (Food Research International 2024, cited 15x) graded on: an animal model — read from the indexed abstract — “rats”
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review or editorial
Collagen peptide supplementation for pain and function: is it effective? (Current Opinion in Clinical Nutrition & Metabolic Care 2022, cited 14x) graded on: indexed as "Review" - secondary literature, not a study — “Review”
Not graded
1 citation whose study design could not be read from the title. Left ungraded rather than guessed at.
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not graded
NCT04420091: Effect of Cartidyss-based Dietary Supplement on Knee Joint Functionality and Discomfort in Adult Population graded on: NCT04420091 is completed and has posted no results - a registration, not a reported outcome — “NCT04420091”
Notes unverified prose
DB RCT: hydrolyzed fish cartilage improved skin morphology; 6-month trial: 3,000 mg/day LMCP reduced knee pain; NCT04420091; Russian bioregulators have no Western validation; (collagen peptide vs glucosamine); no Western RCTs
Not on file 9
8 of the 8 fields we track hold nothing on this record, and each says why. 1 further absence is named below. A blank field is a bug; a named absence is a finding.
- molecular weightnothing we hold supplies it
- molecular formulanothing we hold supplies it
- CAS registry numbernothing we hold supplies it
- PubChem identifiernothing we hold supplies it
- amino-acid sequencenot applicable to this compound
- SMILES stringnothing we hold supplies it
- InChInothing we hold supplies it
- InChI keynothing we hold supplies it
- half-lifenothing we hold supplies it
Each field links to every other record missing the same thing. The full ledger holds 765 gaps across 163 records.