BPC-157

Mechanism

Influences angiogenesis, nitric-oxide signaling, and fibroblast migration.

Reported effects

What sources associate with this compound. Reported categories, not outcomes we have graded — each would need its own citation and rung.

• Systemic repair support
• Gut barrier support
• Tissue regeneration

Reconstitution

mass ÷ diluent = concentration; dose ÷ concentration = volume; volume × the syringe factor = units on the barrel (100 for U-100, 40 for U-40). Run your own numbers.

Reported adverse effects

No controlled human safety data exists.

• Injection site irritation

  Anecdotally reportedonset: Immediatereported reversible

Literature on file 3

• human observational
  NCT02637284: Phase I, Pilot Study in Healthy Volunteers, to Assess the Safety and Pharmacokinetics of PCO-02, Which Active Ingredient is BPC-157, a Penta-deca-peptide From Gastric Source. graded on: a registered clinical study — “clinicaltrials.gov”
• animal in vivo
  The influence of a novel pentadecapeptide, BPC 157, on NG-nitro-l-arginine methylester and l-arginine effects on stomach mucosa integrity and blood pressure (European Journal of Pharmacology 1997, cited 122x) graded on: an animal model — read from the indexed abstract — “Rats”

Not graded

1 citation whose study design could not be read from the title. Left ungraded rather than guessed at.

• not graded
  The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration (Journal of Applied Physiology 2011, cited 100x)

Identity

PubChem CID 9941957 computed 3D conformer

Skeletal formulathe canonical depiction

Drawn by PubChem from CID 9941957, the identifier on this record.

Molecular weight

1419.556

Molecular formula

C62H98N16O22

CAS number

137525-51-0

PubChem CID

9941957

InChI key

HEEWEZGQMLZMFE-RKGINYAYSA-N

Sequence

GEPPPGKPADDAGLV

SMILES

C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H]2CCCN2C(=O)[C@@H]3CCCN3C(=O)[C@@H]4CCCN4C(=O)[C@H](CCC(=O)O)NC(=O)CN

InChI

InChI=1S/C62H98N16O22/c1-31(2)25-37(55(92)74-50(32(3)4)62(99)100)71-46(81)29-65-51(88)33(5)67-53(90)38(26-48(84)85)73-54(91)39(27-49(86)87)72-52(89)34(6)68-57(94)41-15-10-21-75(41)58(95)35(13-7-8-20-63)70-45(80)30-66-56(93)40-14-9-22-76(40)60(97)43-17-12-24-78(43)61(98)42-16-11-23-77(42)59(96)36(18-19-47(82)83)69-44(79)28-64/h31-43,50H,7-30,63-64H2,1-6H3,(H,65,88)(H,66,93)(H,67,90)(H,68,94)(H,69,79)(H,70,80)(H,71,81)(H,72,89)(H,73,91)(H,74,92)(H,82,83)(H,84,85)(H,86,87)(H,99,100)/t33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,50-/m0/s1

Classified as

Nitric Oxide Signalingmechanism

This mechanism links records that otherwise look unrelated, because cardiovascular, sexual health and wound repair claims all run partly through vessel tone and blood delivery.

Fibroblast Migrationmechanism

It is one of the few repair mechanisms with a cheap, clean laboratory readout, which is exactly why so many records here sit on the in_vitro rung and go no higher.

Angiogenesis Modulationmechanism

New vessel growth is one of the concrete, measurable steps in the Wound Healing Cascade, so this is where a repair claim can be traced to something specific rather than left as the word healing.

Gut Barrier Supportmechanism

This mechanism sits underneath most gut records, and it is one where the measurement problem is as important as the finding. A claim is only as good as the permeability assay behind it.

Subcutaneousroute

This is the route the reconstitution arithmetic assumes. Mass divided by diluent volume gives concentration, dose divided by concentration gives volume, and volume in mL multiplied by 100 gives units on a U-100 barrel: 5 mg in 2 mL is 2.5 mg/mL, and 0.25 mg comes out at 0.1 mL, which is 10 units.

Oralroute

Route sets what a milligram means. An oral figure and an injected figure for the same compound are not comparable amounts, and treating one as the other is one of the commonest ways a record gets misread.

Also called

• BPC-157
• BPC-157 (GI)

Listed prices 54

What 46 shops we track listed for BPC-157, read from their own public catalogues on 2026-08-12. We take no commission on these and they are not ranked by any payment — how vendors are scored.

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